@article { author = {Khodkam, Maedeh and Panahi, Delaram}, title = {Guillain-Barré syndrome in remission of Ulcerative colitis: a case report}, journal = {Neurology Letters}, volume = {2}, number = {1}, pages = {13-15}, year = {2023}, publisher = {Iran University of Medical Sciences}, issn = {2821-1723}, eissn = {2821-1723}, doi = {10.52547/nl.2.1.13}, abstract = {This case report provides a unique instance of a patient who developed Guillain-Barré syndrome (GBS) during the remission phase of ulcerative colitis (UC). GBS is a rare but severe autoimmune disorder affecting the peripheral nervous system, while UC is a chronic inflammatory bowel disease. The co-occurrence of GBS and UC is rare, and its underlying mechanisms are not well understood. The patient's medical history and the course of their treatment are discussed in detail to provide a comprehensive understanding of the condition.The onset of GBS in this case report was characterized by lower extremity weakness and numbness of the upper extremities, which is consistent with the typical symptoms of GBS. The electromyography (EMG) results showed low limb nerve conduction and velocity with low amplitude, which supports the diagnosis of GBS. The treatment involved intravenous (IV) methylprednisolone, which is a commonly used steroid in the management of GBS. The patient showed improvement in his symptoms, with the weakness and numbness disappearing and muscle strength recovering, which is in line with the expected outcome of treatment with steroids.This case report provides valuable insight into the complex interplay between GBS and UC, and the potential impact of autoimmune diseases on each other. The findings of this report will contribute to the existing literature on GBS and UC, and help healthcare professionals to make informed decisions regarding the diagnosis and management of these complex conditions. The report concludes with a discussion of the implications of the case and the need for further research to better understand the relationship between GBS and UC.}, keywords = {case report,Guillain–Barré Syndrome,Inflammatory bowel disease,Ulcerative colitis}, url = {https://www.neurologyletters.com/article_170302.html}, eprint = {https://www.neurologyletters.com/article_170302_aeac715f6fcb5f6e798133acc4416e23.pdf} }